Product name      KoVidone^®VA64 Copovidone

USP/EP name      Copovidone, Copovidonum

INCI/CTFA          VP/VA copolymer 60/40

CAS NO.             25086-89-9

K value              25.2-30.8 (Copovidone 28), 27.0-33.0 (Copovidone 30)

Properties          Hygroscopic capacity lower than KoVidone® K30; Soluble in water, alcohol and many other organic solvents; Glass transition temperature(Tg) lower than KoVidone^® K30; Forms transparent, water removable films.

The content of vinyl acetate    35.3-41.0%

Applications

KoVidone^®VA64 possesses excellent powder and film properties for broad application in the pharmaceutical field:

·      Water soluble tablet binder; suitable for wet or dry granulation and direct compression processes, improves particle compressibility.

·      Film-former; permeable film coating for tablet and sugar coatings to protect against splitting, decrease moisture sensitivity and provide good film adhesiveness, elasticity, and hardness.

·      Porogenic agent; for use in taste-masking and component of the matrix material used in controlled-release formulation.

·      Solubilizing agents; for solid dispersion processes to enhancing bioavailability and improve drug solubility. For use in both Hot Melt Extrusion and Spray Solvent Drying